

When combined with other data on the same line and written without the slash, it usually won’t mean not applicable.
If it’s in some sort of published professional context, I wouldn’t read it as not applicable without the slash.
North America is a reasonable guess when specifying region could be context appropriate. Like you said with video game team names, but also company/org names, species common names, or treaties.
AI aside, different voices may be immersion breaking. I tend to avoid audiobooks with more than a single narrator.